Vaccination of cats experimentally infected with feline immunodeficiency virus, using a recombinant feline leukemia virus vaccine. Review of the first feline leukemia virus vaccine. How molecular methods change our views of FeLV infection and vaccination. Joining Europe PMC. Tools Tools overview. ORCID article claiming. Journal list. Grant finder. External links service. Annotations submission service. Developers Developer resources. API case studies. SOAP web service. Annotations API. OAI service.
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Abstract Forty-seven kittens were exposed for 31 weeks to 12 FeLV-positive carrier cats. The carrier cats were infected with 2 laboratory strains of FeLV and at least 2 strains of street virus. Eleven nonvaccinated control kittens and 12 vaccinated kittens were allotted to 3 groups.
After 31 weeks of exposure, the following kittens were persistently blood FeLV positive by ELISA and immunofluorescence antibody IFA testing: 7 of the 11 control kittens, 0 of 12 kittens inoculated with vaccine A, 5 of 12 kittens inoculated with vaccine B, and 6 of 12 kittens inoculated with vaccine C. Only the kittens inoculated with vaccine A were significantly P less than 0. After 23 weeks of exposure, culture was done to identify FeLV in the bone marrow of the kittens.
Feline leukemia virus was isolated from the bone marrow of 9 of 11 control kittens. Virus was isolated from the bone marrow of 5 of 12 kittens inoculated with vaccine A, 11 of 12 kittens inoculated with vaccine B, and 10 of 12 kittens inoculated with vaccine C. Of the 17 cats that had FeLV isolated only from culture of bone marrow negative results of blood virus isolation, ELISA, and IFA testing , 13 eliminated the virus from the bone marrow by week 31 of exposure.
After 31 weeks of exposure, FeLV was isolated from the bone marrow of 8 of 11 control kittens, 0 of 12 kittens inoculated with vaccine A, 7 of 12 kittens inoculated with vaccine B, and 7 of 12 kittens inoculated with vaccine C. Important mammalian veterinary viral immunodiseases and their control. Feline leukemia virus immunity induced by whole inactivated virus vaccination.
Review of companion animal viral diseases and immunoprophylaxis. Re-examination of feline leukemia virus: host relationships using real-time PCR. Similar Articles To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.
Forty-seven kittens were exposed for 31 weeks to 12 FeLV-positive carrier cats. The carrier cats were infected with 2 laboratory strains of FeLV and at least 2 strains of street virus. Eleven nonvaccinated control kittens and 12 vaccinated kittens were allotted to 3 groups.
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